Overall Share of Ocrevus Remains Stable Among Recent New Start Patients, Yet Genentech’s Efforts to Increase First-Line Use Appears to be Paying Off in the Dominant Relapsing-Remitting Multiple Sclerosis Subgroup
Ocrevus cedes substantial ground to off-label glatiramer acetate agents (particularly generics) in the first-line primary progressive multiple sclerosis subgroup, due to a desire for favorable tolerability and pressure from payers, with little hope of redemption coming from potential first switches among these patients, according to Spherix Global Insights’ most recent patient chart audit EXTON, Pa., […]
Amgen/Novartis’ Aimovig Label Revision and Teva’s Ajovy Autoinjector Delay Clear the Way for Continued Growth of Eli Lilly’s Emgality in the US Migraine Prevention Market, According to Spherix Global Insights
Neurologists and migraine specialists believe that a potential dual acute and preventive migraine indication for Lundbeck’s eptinezumab and Biohaven’s rimegepant could be influential in differentiating the pipeline agents from Allergan’s atogepant and the currently marketed CGRP therapies EXTON, Pa., December 18, 2019 ― Eli Lilly’s Emgality, the third anti-calcitonin gene-related peptide (CGRP) therapy to the […]
Lilly Launches Real-World Study to Benchmark Emgality Against Migraine Rivals
From: Fierce Pharma By: Eric Sagonowsky Lilly Launches Real-World Study to Benchmark Emgality Against Migraine Rivals Eli Lilly’s CGRP migraine prevention med Emgality trailed its rivals onto the market, but it’s been a force in the dogfight for market share. Now, in an effort to learn more about how […]
Neurologists Anticipate Overall Expansion of the Fumarate Class Following the US Launch of Biogen’s Vumerity for Treatment in Multiple Sclerosis, According to Spherix Global Insights
While neurologists are eager to believe that Vumerity will provide a superior tolerability profile over Biogen’s own Tecfidera, increasing first-line use of Genzyme’s Aubagio, Novartis’ Mayzent, and Genentech’s Ocrevus could present additional competitive pressure in the crucial new start patient segment EXTON, Pa., December 10, 2019 ― Biogen’s Vumerity (diroximel fumarate), a monomethyl fumarate prodrug, […]
Ocrevus Top Choice of US Neurologists for Active SPMS, But Mayzent and Mavenclad Gaining Interest, Report Says
From: Multiple Sclerosis News Today By: Ana Pena, PHD Ocrevus Top Choice of US Neurologists for Active SPMS, But Mayzent and Mavenclad Gaining Interest, Report Says Genentech‘s Ocrevus (ocrelizumab) continues to be the most prescribed medication to reduce inflammatory disease in people with active secondary progressive multiple sclerosis (SPMS) among U.S. neurologists, even though Novartis’ Mayzent (siponimod) and EMD Serono’s Mavenclad (cladribine) were […]
Opportunity for EMD Serono’s Mavenclad is Growing in the Relapsing-Remitting Multiple Sclerosis Segment of the Canada Market, Although Increasingly Deferred Treatment Algorithm Positioning Is a Threat That Could Benefit Roche’s Ocrevus and Novartis’ Gilenya
With neurologists eagerly waiting for approval of Mayzent and interest growing in ofatumumab, Novartis is seen as a highly credible company with the potential to offer a diverse multiple sclerosis portfolio, according to Spherix Global Insights EXTON, Pa., November 19, 2019 ― Once approved by Health Canada and accessible on provincial drug formularies, the Canadian […]
Novartis’ Mayzent and EMD Serono’s Mavenclad Look to Dethrone Genentech’s Ocrevus in the Expanding Patient Segment of Active Secondary Progressive Multiple Sclerosis
Following the recent relapsing forms of MS indication revision by the FDA, the unmet need for not active SPMS therapy has been put into stark contrast to other subtypes, while skepticism remains regarding the potential for MedDay Pharmaceuticals’ Qizenday, AB Science’s masitinib, or MediciNova’s ibudilast to emerge as the first-to-market solution, according to Spherix Global […]
Mavenclad, Ocrevus Use Rising in EU as Injectables and Tysabri Decline, Spherix Reports
From: Multiple Sclerosis News Today By: Ana Pena, PHD Mavenclad, Ocrevus Use Rising in EU as Injectables and Tysabri Decline, Spherix Reports Prescriptions of two multiple sclerosis (MS) treatments — Merck KGaA‘s Mavenclad (cladribine) and Roche‘s Ocrevus (ocrelizumab) — have been rising in Europe over the past six months, bolstered by greater market […]
Benefitting From Expanded Access in Europe, Roche’s Ocrevus is on Track to Displace Biogen’s Tysabri in Neurologist Preference and Share Among Patients with Relapsing Forms of Multiple Sclerosis Over the Next Six Months
Italian and Spanish neurologists’ recent embrace of Merck KGaA’s Mavenclad, combined with a shift from Sanofi’s Lemtrada in the UK to Mavenclad, has helped boost share of the high-efficacy oral therapy, according to the 5th wave of the twice-yearly Spherix Global Insights report EXTON, Pa., October 7, 2019 ― Expanded access to Merck KGaA’s Mavenclad […]
Strong Uptake in the Expanding Preventive-Treated Episodic Migraine Segment Has Propelled Eli Lilly’s Third-to-Market Emgality to Second Place in the Anti-CGRP Class ― Surpassing Teva’s Ajovy
Allergan’s Botox appears indifferent to the chatter surrounding the anti-CGRP class launch, benefitting from high patient awareness and switch business opportunities following anti-CGRP discontinuations, according to the fifth wave of the quarterly Spherix Global Insights series EXTON, Pa., September 26, 2019 ― Nine months post launch, specialists’ self-reported share for Eli Lilly’s Emgality has surpassed […]
